WebIn BOD1L-depleted cells, damaged forks were slower to restart and/or were more susceptible to stalling, and they were vulnerable to resection by DNA2 (601810). … Web48 resection catalysed by Exo1 (9, 15–17). Spo11-oligo complexes are formed in an 49 evolutionarily divergent yeast, Schizosaccharomyces pombe (18), and are also …
Annabel Quinet - ATIP-Avenir Team leader - INSERM LinkedIn
WebEnd resection: 5 -3 nucleolytic degradation of DSB ends MRX/N: Mre11-Rad50-Xrs2/Nbs1 complex STR: Sgs1-Top3-Rmi1 complex PIKK: PI3K-like kinase ATM: ataxia … WebVandaag · Oxidized bases are resolved primarily by base excision repair (BER), whereas the DNA backbone is repaired by SSB repair or ... (CtIP). DSB breaks are sealed by … boc life ceo
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Web4 nov. 2008 · It is also evident that at equivalent concentrations of the DNA strand exchange proteins, hRad51 limited nucleolytic resection by hExo1–BLM most effectively . … WebThe roles of these proteins in nucleolytic DSB resection are well characterized, but their role in bridging the DNA ends for efficient and correct repair is much less explored. Here … WebThe repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is initiated by nucleolytic resection of the DNA break ends. The current model, being … boc lifestyle