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WebJun 11, 2024 · Insect odorant receptors (ORs) have been suggested to function as ligand-gated cation channels, with OrX/Orco heteromers combining ionotropic and metabotropic activity. The latter is mediated by different G proteins and results in Orco self-activation by cyclic nucleotide binding. In this contribution, we co-express the odor-specific subunits … WebOct 27, 2016 · Genealogical relationship between Hymenopteran olfactory receptor families (A-P, 9-exon, Orco) and the Drosophila olfactory receptors identified from the present screen (n = 4, incl. Orco). Red ...
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WebJun 16, 2011 · Insect odorant receptors (ORs) have a unique design of heterodimers formed by an olfactory receptor protein and the ion channel Orco. Heterologously expressed insect ORs are activated via an ionotropic and a metabotropic pathway that leads to cAMP production and activates the Orco channel.
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