Phosphogluconolactonase

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August undefined, 2024

WebApr 14, 2024 · Pseudomonas cannabina pv. alisalensis (Pcal) causes bacterial blight on cabbage. We previously conducted a screening for reduced virulence using Tn5 transposon mutants and identified one of the transcriptional factors, HexR, as a potential Pcal virulence factor. However, the role of HexR in plant pathogenic Pseudomonas virulence has not … Web6-phosphogluconolactonase: ( fos'fō-glū'kŏ-nō-lak'tō-nās ), A hydrolase that catalyzes the hydrolysis of 6-phospho- d -glucono-δ-lactone to produce 6-phospho- d -gluconate; this enzyme is a part of the pentose phosphate shunt.

Listeria monocytogenes 6-Phosphogluconolactonase Mutants …

WebNational Center for Biotechnology Information Web6-Phosphogluconolactonase (6PGL, PGLS) is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the … css professional

6-Phosphogluconolactonase - Creative Enzymes

WebApr 15, 2024 · IntroductionThe pentose phosphate pathway (PPP) is essential for NADPH generation and redox homeostasis in cancer, including glioblastomas. However, the precise contribution to redox and tumor proliferation of the second PPP enzyme 6-phosphogluconolactonase (PGLS), which converts 6-phospho-δ-gluconolactone to 6 … WebFunction Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. Catalytic activity 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H+ 1 publication EC:3.1.1.31 ( UniProtKB ENZYME Rhea) Source: Rhea 12556 Hide Rhea reaction 6-phospho- D -glucono-1,5-lactone CHEBI:57955 zoom + H 2 O CHEBI:15377 zoom = 6 … css professional resources

6-phosphogluconolactonase - Wikipedia

WebInfobox references. 6-Phosphogluconolactone is an intermediate in the pentose phosphate pathway (PPP). In the PPP pathway, it is produced from glucose-6-phosphate by glucose … WebSynonym (s): Anti-6PGL)] antibody produced in rabbit, Anti-GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase antibody produced in … css profesional6-Phosphogluconolactonase (EC 3.1.1.31, 6PGL, PGLS, systematic name 6-phospho-D-glucono-1,5-lactone lactonohydrolase) is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the oxidative phase of the pentose … See more 6PGL hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid has been proposed to proceed via proton transfer to the O5 ring oxygen atom, similar to xylose isomerase See more 6PGL in Homo sapiens exists as a monomer at cytosolic physiological conditions, and is composed of 258 amino acid residues with a total molecular mass of ~30 kDa. The tertiary structure of the enzyme utilizes an α/β hydrolase fold, with both parallel and … See more • 6-phosphogluconolactonase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Collard F, Collet JF, Gerin I, Veiga-da-Cunha M, Van Schaftingen E … See more 6-phosphogluconolactonase catalyzes the conversion of 6-phosphogluconolactone to 6-phosphogluconic acid, both intermediates in the oxidative phase of the pentose phosphate pathway See more Malarial parasites Plasmodium berghei and Plasmodium falciparum have been shown to express a bi-functional enzyme that exhibits both See more css privilegium san fernando

"WebMar 21, 2024 · The enzyme 6-phosphogluconolactonase catalyses the second step of this pathway, converting 6-phosphogluconolactone to 6-phosphogluconic acid. This enzyme has been known to have a significant involvement in growth, pathogenesis and sensitivity to oxidative stress in bacterial and protozoal pathogens. " - Phosphogluconolactonase

Phosphogluconolactonase

γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose ...

WebPhosphoglucomutase. Phosphoglucomutase ( EC 5.4.2.2) is an enzyme that transfers a phosphate group on an α-D- glucose monomer from the 1 to the 6 position in the forward direction or the 6 to the 1 position in the reverse … Web6-Phosphogluconolactonase was purified to apparent homogeneity in a four-step procedure from bovine erythrocytes. The extent of purification and the kinetic properties of the …

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WebFunction Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. Catalytic activity 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H+ 1 publication … WebMay 20, 2009 · The PPP contains a series of reactions catalyzed by seven different enzymes: glucose-6-phosphate 1-dehydrogenase (G6PDH), 6-phosphogluconolactonase (6PGL), 6-phosphogluconate dehydrogenase (6PGDH), ribose-5-phophate isomerase (RPI), ribulose-5-phosphate 3-epimerase (RPE), transketolase (TK) and transaldolase (TA) …

Web6-Phosphogluconolactonase (6PGL, PGLS) is a cytosolic enzyme found in all organisms that catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconic acid in the oxidative phase of the pentose phosphate pathway. [2] WebAug 1, 2011 · Glucose-6-phosphate dehydrogenase (G6PD) is the first enzyme of the pentose phosphate pathway, a conserved pathway responsible for producing a variety of …

WebMar 25, 2013 · The oxidative section of the PPP (oxPPP) converts glucose-6-P into ribulose-5-P. Glucose-6-P dehydrogenase (G6PDH, EC 1.1.1.49) and 6-phosphogluconate dehydrogenase (6PGDH, EC 1.1.1.44), catalyse the irreversible oxidation of glucose-6-P, generating two molecules of NADPH and one molecule of CO 2. WebSynonym (s): Anti-6PGL)] antibody produced in rabbit, Anti-GDH/6PGL endoplasmic bifunctional protein precursor [Includes: Glucose 1-dehydrogenase antibody produced in rabbit, Anti-Hexose-6-phosphate dehydrogenase); 6-phosphogluconolactonase antibody produced in rabbit. Compare. Product No. Clonality. Application. Species Reactivity.

WebJan 25, 2024 · In Plasmodium, a bifunctional enzyme named glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase (GluPho) catalyzes the first two steps of the PPP. PfGluPho has been shown to be essential for the growth of blood stage Plasmodium falciparum parasites.

WebA newly observed phenotype of pgl strains is a lowered frequency of appearance of Bgl+ mutants that can utilize the beta-glucoside salicin. This is likely due to poor growth of Bgl+ pgl strains on salicin due to the accumulation of 6-phosphogluconolactone. MeSH terms Carboxylic Ester Hydrolases / chemistry Carboxylic Ester Hydrolases / genetics* css profile 2022-23WebAug 1, 2011 · Fusions of the first two enzymes in the pentose phosphate pathway, glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconolactonase (6PGL), have been previously described in two distant clades, chordates and species of the malarial parasite Plasmodium. We have analyzed genome and expressed sequence data from a variety of … earls reginaWebMar 21, 2024 · The hexose monophosphate shunt is a crucial pathway in a variety of microorganisms owing to its vital metabolic products and intermediates such as NADPH, … css profile 2020 2021 pdfWebNational Center for Biotechnology Information earls red hotelWebOct 26, 2024 · Here, by analyzing the liver cell single-cell sequencing data from HCC patients and healthy individuals, we found that 6-phosphogluconolactonase (PGLS), a cytosolic … earls redWebDec 19, 2024 · The second enzyme in the oxiPPP, 6-phosphogluconolactonase (PGLS), converts 6PGL to 6-phosphogluconate (6PG). The third enzyme in the pathway, 6PGD, … css profile 1839WebMay 20, 2009 · The PPP contains a series of reactions catalyzed by seven different enzymes: glucose-6-phosphate 1-dehydrogenase (G6PDH), 6-phosphogluconolactonase … css profile 2023 24